# Do Botox, Dysport, Xeomin and Myobloc use the same billing units?

Canonical: https://prospyrmed.com/resources/practice-answers/botulinum-toxin-j-codes
Sources reviewed: 2026-09-16 · Prepared by Prospyr

No. Their drug identifiers and billing increments differ, and product potency units are not a clinical conversion formula. Check the exact product’s HCPCS definition and prescribing information. Never infer an equivalent treatment dose by dividing or multiplying the billing increments.

## Build a product-specific charge reference

The CMS article identifies J0585 for onabotulinumtoxinA, J0586 for abobotulinumtoxinA, J0587 for rimabotulinumtoxinB and J0588 for incobotulinumtoxinA. The billing increments differ: respectively 1, 5, 100 and 1 product units. This is a selected reference, not an exhaustive current code set.

Source: [CMS: Billing and Coding — Botulinum Toxins (A52848)](https://www.cms.gov/medicare-coverage-database/view/article.aspx?articleid=52848) — Medicare contractor article; verify jurisdiction and date of service

## Separate coding from prescribing

BOTOX prescribing information states that its potency units are specific to the product and assay and are not interchangeable with other toxin preparations. A billing worksheet must not double as a treatment conversion chart. Product substitutions require clinical review and a fresh billing check.

Source: [AbbVie: BOTOX prescribing information](https://www.rxabbvie.com/pdf/botox_pi.pdf) — Manufacturer prescribing information

## Practical checklist

1. Match brand and nonproprietary name to the actual package.
2. Verify the current code and increment with a licensed coding reference.
3. Maintain separate inventory and charge entries for each product.
4. Review substitutions with the clinical and billing leads before use.

## Worked example

A practice adds a second toxin brand. Copying the first product’s charge entry can carry over the wrong unit increment even when the label looks familiar. Create a separate product row with code, increment, source date and reviewer; leave clinical dosing to the treating professional.

## Mistakes to avoid

- Using “Botox” as the inventory name for every toxin.
- Turning reimbursement units into equivalent clinical doses.
- Assuming this selected list includes every newly approved product.

## Related questions

- [How do you calculate J0585 billing units for Botox?](https://prospyrmed.com/resources/practice-answers/j0585-botox-billing-units)
- [Do drug claims need an 11-digit or 12-digit NDC?](https://prospyrmed.com/resources/practice-answers/ndc-format-drug-billing)
- [What should an injectable lot and recall log track?](https://prospyrmed.com/resources/practice-answers/drug-lot-recall-tracking)

Prepared by Prospyr from the cited primary sources. These are educational workflow resources, not individualized clinical, coding, legal or tax advice. No clinician, certified-coder or attorney review is claimed. Confirm current code instructions, payer terms and applicable law for the actual service and date. CPT is a registered trademark of the American Medical Association; this is not a substitute for a licensed current code set.