Best Professional Microneedling Pens for Med Spas (2026): 7 Compared

For med spa owners, medical directors and lead aestheticians. Updated October 11, 2026 · Prepared by Prospyr. Prospyr makes practice software, not aesthetic devices, and none of the manufacturers below is a Prospyr product or partner. Each summary reflects what the company publishes on its own website, checked October 2026, cross-checked against the FDA's 510(k) database for powered microneedle devices (product code QAI). Specifications, indications, pricing and service terms change, so get every number in writing from a sales rep before you buy.

What does a professional microneedling pen do?

A professional microneedling pen is a powered handpiece that drives a sterile, single-use cartridge of fine needles in and out of the skin at a set depth and speed, creating controlled micro-channels. Unlike RF microneedling devices, it delivers no heat or energy. The FDA classifies these as powered microneedle devices, and each cleared pen has a specific indication, usually facial acne scars or certain wrinkles in adults 22 and older. Pens differ in four ways that matter to a med spa: the cleared indication, the cartridge options and cost, how the pen guards against fluid backflow, and what training and marketing support come with it.

The 7 professional microneedling pens at a glance

How we chose this list

We looked for companies that sell a powered microneedling pen to US practices and checked each against the FDA's 510(k) database for product code QAI. We then compared four things a practice manager can confirm before a demo: the cleared indication, the cartridge and depth details the company publishes, what it says about cross-contamination and reprocessing, and whether training or a provider program is described. We left out RF microneedling, home-use rollers and pens sold without a stated FDA clearance. The order is our editorial view, not a measure of results.

1. Crown Aesthetics (SkinPen Precision Elite and MicroPen EVO)

Crown Aesthetics, which its site describes as a Revance company and the FDA database lists in Dallas, Texas, sells two cleared pens. SkinPen Precision was the device behind the FDA's 2018 De Novo grant (DEN160029, to Bellus Medical) that created the powered microneedle device category. Crown's site calls SkinPen Precision "the first FDA-cleared microneedling device approved for use on the face and an area of the body" (Crown's wording; the device is FDA-cleared, not approved). SkinPen Precision Elite, cleared in August 2024 (K241400), is the current model; its cleared indication covers wrinkles of the neck in Fitzpatrick skin types II to IV and facial acne scars in adults of all Fitzpatrick skin types aged 22 and older.

What stands out:

• Neck depth. Crown states SkinPen Precision can be used at a depth of up to 2.5 mm on the neck.
• Second pen. Crown also sells MicroPen EVO, which it says is FDA-cleared for neck wrinkles and facial acne scars in people 22 and older; the FDA database lists that indication under K212558 (2021), submitted by Eclipse Medcorp. It lists a 7,000 RPM piston, a touch-free cartridge connection, a Teflon gear seal to keep fluid out of the pen body, and a cordless lithium-ion battery rated for more than four hours, with two batteries included.
• Provider program. Both product pages point to a "Become A Provider" path rather than online ordering.

Right for: practices that want the pen patients most often ask for by name. Ask: which of the two pens fits your treatment menu, the cartridge price, and what the provider program requires.

2. MT.DERM (Exceed Unlimited)

MT.DERM, based in Berlin, Germany, sells the Exceed Unlimited under its amiea med brand. It states the pen holds FDA clearance K233709 (February 2024) for wrinkles in the glabellar, periorbital and cheek-fold areas in adults 22 or older with Fitzpatrick skin types I to III, and for facial acne scars in adults 22 or older with skin types I to IV. MT.DERM says the earlier Exceed was the first medical microneedling device with dual FDA clearance.

What stands out:

• Specifications. Six-needle sterile cartridges, frequency up to 150 Hz, maximum penetration limited to 1.5 mm when used as intended, and a stated depth precision of plus or minus 0.15 mm.
• No energy. MT.DERM states the pen delivers no RF energy or intentional heat.
• Training. It runs a Medical Microneedling Academy online and offers protocols after a demo request.

Right for: practices that want one pen cleared for both wrinkles and acne scars. Ask: who sells and services Exceed in the US today, since the page notes availability differs by country, and the cartridge cost per treatment.

3. SkinStylus (SteriLock MicroSystem)

SkinStylus sells the SteriLock MicroSystem. Its site states indications for facial acne scars in Fitzpatrick skin types I to III in patients 22 and older, and surgical or traumatic hypertrophic scars on the abdomen in adults 22 or older. The most recent clearance in the FDA database, K253002 (February 2026, Esthetic Medical, Inc.), also adds periorbital wrinkles in Fitzpatrick skin types I to VI in adults 34 or older. SkinStylus notes that only the 36-pin cartridge may be used for facial acne scars.

What stands out:

• Reprocessing. SkinStylus states the nosecone can be disinfected with CaviCide or autoclave-reprocessed without a plastic sheath, and describes a patented seven-step cartridge safety system against cross-contamination.
• Kit contents. The system page lists corded and cordless operation, two nosecones, two lithium-ion batteries and three cartridges (12-pin, 36-pin and 36-pin HiLo), with depth cleared to 2.5 mm.

Right for: practices, including those near plastic surgery referrals, that want an abdominal scar indication. Ask: whether the periorbital wrinkle indication is in the labeling of the units it ships today, the warranty length in writing (the home page and system page list different terms), and the price per cartridge type.

4. Collagen P.I.N.

Collagen P.I.N., with a corporate office in Louisville, Kentucky, describes its pen as FDA-cleared to improve the appearance of facial acne scars in adults 22 and older with Fitzpatrick skin types I to III. The FDA database lists the clearance (K222199, October 2022) under Induction Therapies, LLC. The company lists a 36-pin cartridge, an adjustable depth dial from 0.1 to 3.0 mm, cordless operation and an airflow design it says avoids dragging or suction.

Right for: practices building an acne scar program that want a high pin count. Ask: cartridge price, what training comes with the pen, and the terms behind the financing application linked on its site.

5. Refine USA (Rejuvapen NXT)

Refine USA, based in Jacksonville Beach, Florida, makes the Rejuvapen NXT, which it says is manufactured in the USA and cleared under K192138 (April 2020). Its stated intended use is to improve the appearance of periorbital wrinkles in Fitzpatrick skin types I to IV; the FDA clearance adds that it is for adults at least 22 years old. Refine lists 12 stainless steel needles in a circular arrangement, a depth dial from 0.02 to 2.5 mm, nine speed settings from 80 to 110 Hz, and a plug-in design it says avoids battery fade.

Right for: practices that want a US-made, corded pen and treat the eye area often. Ask: for the cartridge price in writing, and how you may describe treatments outside the periorbital indication in your marketing.

6. Dermalogica (PRO Pen)

Dermalogica, the professional skincare company, sells the PRO Pen Microneedling System to skin professionals. Its professional site calls PRO Pen "a Class II, FDA 510(k) cleared medical device" to improve the appearance of facial acne scars, and the FDA database lists the clearance (K243800, August 2025) for facial acne scars in adults 22 and older. The page describes a 14-pin cartridge and an adjustable depth control ring but gives no numeric depth range.

Right for: skin-health practices and estheticians who already buy Dermalogica and want a pen that fits that protocol. Ask: who may operate the pen under your state rules, the account requirements, and the cartridge and device cost.

7. DermapenWorld (Dermapen 4)

DermapenWorld sells Dermapen 4 to Authorised Treatment Providers and lists partner practices in a public finder. It states adjustable depths up to 3 mm and a dedicated scar treatment setting. Its FAQ cites 510(k) number K221070, which the FDA database lists as the DP4 Microneedling device, cleared in December 2022 to Equipmed USA, LLC, for facial acne scars in Fitzpatrick skin types I to V in adults 22 or older. DermapenWorld's pages describe this as FDA "approval"; it is a 510(k) clearance.

Right for: practices that want the referral visibility of a branded provider network. Ask: how its treatment pages for other concerns relate to the cleared acne scar indication, the cartridge price, and what the provider agreement requires.

Questions to ask any microneedling pen company

1. What is the 510(k) number and cleared indication? Look it up yourself in the FDA's 510(k) database. Keep your marketing claims inside the cleared indication.
2. What does each treatment cost you? Get the cartridge price, whether cartridges are locked to the pen, and how many you use per area.
3. How does the pen prevent cross-contamination? Ask how fluid is kept out of the motor, what must be single-use, and what your team must clean or autoclave between patients. Add the steps to your OSHA and bloodborne pathogen training.
4. What training is included? Ask how many providers are trained, whether it is in person, and whether new hires can be trained later at no cost.
5. What happens when it breaks? Get warranty length, loaner policy and repair turnaround in writing.
6. Who may perform microneedling in your state? Rules on who may treat and under what supervision vary widely. See our state-by-state microneedling guide and confirm with your medical director.
7. Is it bought outright or financed? Ask for the full payment schedule. For outside lenders, see our list of aesthetic equipment financing companies.

Where Prospyr fits

A microneedling pen earns its keep when patients come back for the full series. Prospyr lets a practice sell microneedling as a series through packages, track cartridge use against each visit in inventory management, and chart depth, pass count and area in the aesthetic EMR so the next provider can repeat the settings. To see that with your treatment menu, book a practice demo.

For the photos that show progress across a series, see our list of before-and-after photo setups. For post-treatment retail, see scar and aftercare product lines.

Frequently asked questions

Which microneedling pen is best for a new med spa?

There is no single best pen; the right one depends on the indication you plan to market, your budget and your team. A newer practice often benefits from a cleared indication that matches its treatment menu, included in-person training, and a cartridge price in writing. Ask at least three companies for a written quote with cartridges and service included.

How much does a professional microneedling pen cost?

None of the seven companies on this list publishes a device price. Ask each one for the device price, cartridge price, warranty and training cost together, because cartridges are the cost you pay on every treatment.

Are microneedling pens FDA approved?

The pens on this list are FDA-cleared, not approved, even where a company's site uses the word "approved." The original SkinPen was authorized through a De Novo request in 2018, and the others were cleared through the 510(k) pathway as powered microneedle devices, each for a specific indication such as facial acne scars or certain wrinkles in adults 22 and older. Check the number in the FDA's database and keep your claims within it.

What is the difference between a microneedling pen and RF microneedling?

A microneedling pen creates micro-channels with needles alone. RF microneedling adds radiofrequency energy at the needle tips to heat the dermis, and those systems cost more and carry different clearances. See our list of RF microneedling devices for that category.

Want your company considered?

We review this list quarterly. Companies that make or distribute FDA-cleared microneedling pens for med spas can send their website and what they offer practices to info@prospyrmed.com. Inclusion is editorial and not paid.

Editorial scope

This list is based on each company's public website and the FDA's 510(k) database, checked October 2026 with AI-assisted research. Companies did not review this article before publication. It is not a guarantee of results or a substitute for checking references, FDA clearances and your state's scope-of-practice rules. Read our methodology or report a correction.