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Lip Filler Aftercare Instructions (Printable Handout)

Lip filler aftercare is short: use a cold compress for swelling, skip hard exercise, sun and heat for 24 hours, avoid aspirin, NSAIDs and blood thinners for a week, and expect swelling and bruising that usually clear in one to two weeks. This page builds a printable lip filler aftercare instructions handout from FDA patient labeling.

Prepared by Prospyr · Reviewed October 3, 2026 · Free, no sign-up, runs in your browser

Template — review and edit with your medical director before giving to patients.

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Your practice

Printed at the bottom of the handout. Clear it to leave it off.

The first 24 hours

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The first week

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What to avoid

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Call us if

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Notes and footer

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Your practice name

After your lip filler treatment

Swelling, tenderness and some bruising are common after lip filler. Most settle in one to two weeks. These steps help you heal and tell you when to call.

The first 24 hours

  • For swelling, hold a clean cloth dipped in cold water and wrung out against the lips. An ice pack over the swollen area also works.
  • Do not touch the treated area for the first six hours, so you do not hurt skin that is still numb. After that, wash gently with soap and water.
  • Skip hard exercise, and stay out of excessive heat, sun and UV lamps for the first 24 hours.
  • We will tell you when you can put on lipstick or lip products: ______________________

The first week

  • Redness, tenderness, swelling, firmness, small lumps or bumps, bruising and itching are common.
  • Most of these go away within one to two weeks. In the Restylane Kysse study most were mild or moderate and lasted 7 days or less.
  • Until redness and swelling are gone, protect the area from intense cold and heat, sun lamps and sunbathing.
  • Tell us before you book any laser, peel, microneedling or hair removal near the treated area.

What to avoid

  • Aspirin, NSAIDs such as ibuprofen, St. John's Wort, blood thinners and high-dose vitamin E for one week after treatment, since they can increase bruising. Call us before you change a medicine a doctor prescribed.
  • Tanning beds, sun lamps and excessive sun until redness and swelling are gone.
  • Strenuous exercise for at least the first 24 hours.

Call us if

  • Call 911 or go to an emergency room right away for vision changes, signs of a stroke (sudden trouble speaking, numbness or weakness in the face, arms or legs, trouble walking, a drooping face, severe headache, dizziness or confusion), or skin that looks white.
  • Unusual pain during or soon after the treatment, or significant pain away from the injection site.
  • Signs of infection: fever, redness that spreads, drainage, or tenderness or pain that keeps increasing.
  • Blisters or sores that keep coming back. They can signal a herpes infection.
  • Swelling or other reactions that last more than 14 days, or any problem that shows up weeks or months later.

In an emergency, call 911.

Guidance based on: Restylane Kysse patient information (FDA PMA P140029); Juvederm Voluma XC patient labeling (FDA PMA P110033); AAD: Fillers: FAQs.

Template from prospyrmed.com/tools/lip-filler-aftercare

Template — review and edit with your medical director before giving to patients. General patient information only. It does not replace your provider's instructions or medical advice.

Lip filler aftercare instructions: how long swelling and bruising last

The table shows what published sources say to expect, and where each line comes from. The editor above uses the same lines. Your own protocol, device and product come first.

WhenWhat to expectSource
First 6 hoursDo not touch the lips, since the area may still be numb. A cold compress can go on right after treatment.Restylane Kysse labeling
First 24 hoursMinimize strenuous exercise and excessive sun or heat. These can increase redness, swelling and itching.Kysse and Voluma XC labeling
Days 1 to 7Swelling, tenderness, firmness, lumps, bruising and itching are common. Avoid aspirin, NSAIDs and blood thinners for one week.Restylane Kysse labeling
Days 7 to 14Most injection-site reactions clear in one to two weeks. Reactions that persist beyond 14 days are a reason to call.Restylane Kysse labeling; AAD
Weeks 2 to 4In the Voluma XC (cheek) study most side effects lasted 2 to 4 weeks, and some lasted longer than 30 days.Juvederm Voluma XC labeling

The label wording differs by product, so edit the dates to fit

FDA patient labeling is written per product. Restylane Kysse, which is indicated for the lips, says to cool the area, avoid touching it for six hours, avoid aspirin and similar agents for one week, and minimize exercise, sun and heat for 24 hours. The Juvederm Voluma XC label says to minimize exercise and sun or heat for 24 hours and to ask the doctor when makeup can go on.

The AAD fillers page says to wait until the next day to exercise and to avoid touching the treated area for three days. Those differ from the six-hour rule on the Kysse label. The template uses the label for the product it quotes. If you inject a different lip product, check its patient labeling and change the lines to match.

Lip filler swelling: what is normal and what is a call

Swelling, tenderness, firmness, lumps and bumps, bruising, itching and discoloration are listed as common injection-site responses on the Kysse label. They are the reason the first-week section says what normal looks like.

Vision changes, signs of a stroke, white-looking skin and unusual pain are listed on the label as reasons to call a doctor immediately. The handout puts them first in the call-us list and tells the patient to call 911 or go to an emergency room. Do not shorten that line.

How to edit and print your lip filler handout

  1. Add your practice name and phone number. Both print at the top and bottom of the handout.
  2. Read each line. Uncheck what does not match your protocol, rewrite what needs your wording, and fill in the blanks marked "Fill in".
  3. Add your own lines for products, follow-up dates or anything specific to your devices.
  4. Show it to your medical director. Then print it, save it as a PDF, or copy it as plain text for your patient portal or a text message.

Your text stays in your browser. Only the practice name and phone are saved in the page address, so you can bookmark or share the link with your team.

Once the handout is final, it works best when it goes out automatically. Prospyr's digital intake and charting keep each patient's instructions with their visit, and the med spa software page shows how the rest of the practice fits around them. For related handouts, see the Sculptra aftercare template and the Botox reconstitution calculator.

What this template leaves out

  • Hyaluronidase or any treatment of complications. That is clinical care, not patient aftercare.
  • Product-specific volumes, depths and touch-up timing.
  • Dental work, flying and other situations the labeling does not address. Add your own lines if your protocol covers them.

It is a template to review and edit with your medical director before giving it to patients. It is not medical advice, and it does not replace your provider's instructions for a specific patient.

Frequently asked questions

What are the aftercare instructions for lip filler?

Apply a cold compress, avoid touching the lips for the first six hours, skip hard exercise, sun and heat for 24 hours, and avoid aspirin, NSAIDs and blood thinners for a week. These come from the Restylane Kysse patient labeling. Your provider's product and protocol come first.

How long does swelling last after lip filler?

Most injection-site reactions, including swelling, bruising and tenderness, clear within one to two weeks, per the Restylane Kysse patient labeling. The AAD says 7 to 14 days. Swelling or other reactions beyond 14 days is a reason to call the practice.

Can I exercise after lip filler?

Minimize strenuous exercise for the first 24 hours, according to both the Kysse and Voluma XC labels. The AAD says to wait until the next day. Put your practice's rule on the handout.

Can I wear lipstick after lip filler?

The Voluma XC label says to ask your doctor when makeup can be applied. The template leaves a blank for your own timing instead of inventing one.

What should I avoid after lip filler?

Avoid aspirin, NSAIDs, St. John's Wort, blood thinners and high-dose vitamin E for one week, plus strenuous exercise, sun lamps, tanning beds and intense heat or cold until redness and swelling are gone. Patients should not stop a prescribed medicine on their own, so the handout says to call you first.

When should I call about my lip filler?

Call 911 or go to an emergency room for vision changes, signs of a stroke or white-looking skin. Call the practice for unusual pain, signs of infection, recurring blisters, or swelling that lasts beyond 14 days. These come straight from the Kysse patient labeling.

Sources and scope

Template — review and edit with your medical director before giving to patients. General patient education for lip filler; it does not replace a provider's instructions. Sources reviewed October 2026.

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